Skip to content

Not medical advice. Talk to your provider before using any peptide.

Full disclaimer

Peptide Schedule Research TeamReviewed Apr 7, 20269 Citations

Semax peptide icon, one bubble per amino acidSemax7 residuesMEHFPGPEach bubble = one amino acid. Size = residue mass. Color = chemical class.

Semax Dosage Calculator

Cognitive · Research · Grade B · ~2-3 min half-life · Injection / Nasal

Calculate your dose

Adjust vial, water and dose. The answer updates live.

mL
Dose
Syringe

All three take the same units for the same dose. A smaller barrel just spreads it over more space.

↓ 8.0020406080100
Draw to 8.0 units= 0.080 mL

on a U-100 syringe for a 200 mcg dose

Concentration
2,500
mcg/mL
Doses / vial
25
Cost / dose
$1.08
Market est. ·
Your mixing recipe

Add 2 mL BAC water to your 5 mg vial. Draw to 8.0 units on a U-100 syringe for a 200 mcg dose. This vial will last 25 doses.

Copy link saves these numbers in the address. Anyone who opens it sees the same draw.

Dose math and a schedule you can keep.

Syringe units in one tap. A free account adds dose reminders and calendar sync, plus alerts on the peptides you save.

Track every dose with reminders and a calendar.

  • Dose remindersPush or calendar alarm
  • Peptide alertsFor peptides you save
  • Calendar syncApple, Google, Outlook
  • Supply countsDoses left per vial

Your plans, logs and saved peptides sync to every device.

Opens a preview of your schedule first. The calculator stays free.

Your logs and saved lists are never sold, and not shared except where you choose.

What you need to mix this6 items, matched to your vial, BAC water and syringe
  • Semax, 5 mg vialThe vial size set in the calculator.
  • Bacteriostatic water, 2 mLPrescription-only in the US, so it is dispensed by a pharmacy on a clinician's prescription.
  • 1 mL U-100 insulin syringe (100 units)Matches the syringe set in the calculator. Use a new sterile one for every injection.
  • Alcohol swabsFor each vial stopper every time a needle goes in, and for the injection site. Let the alcohol dry first.
  • A sharps containerUsed syringes go in right after each injection, never loose in the trash.
  • Storage after mixingRefrigerate at 2-8°C, use within 3-4 weeks. Nasal spray: refrigerate after opening, use within 30 days.

How to choose each item: the peptide supplies guide.

Open Semax details
Side effects, protocols by goal, storage, and the sources behind these dosing numbers.

About Semax

Turns your vial size, BAC water, and dose into exact syringe units. Free to use.

Semax triples hippocampal BDNF in rodent models and is approved for stroke recovery in Russia. Short 10 to 20 day intranasal or subcutaneous cycles produce focus and memory benefits that persist weeks after stopping. No RCTs in healthy adults exist.

NootropicACTH AnalogBDNF EnhancerNeuroprotectiveCognitive Enhancement
Subcutaneous or Nasal. Typical beginner frequency: daily.At beginner dose (200 mcg) with a 5mg/2mL vial: draw to the 8-unit mark on a U-100 syringe.
After reconstituting, store at 2-8°C (36-46°F). Refrigerate at 2-8°C, use within 3-4 weeks. Nasal spray: refrigerate after opening, use within 30 days.

View side effects and safety warnings →

Quick-Start: Reconstitution

  1. 1Reconstitute the vial. Add 2 mL of bacteriostatic water to a 5 mg Semax vial. This gives you 2500 mcg/mL. Swirl gently, do not shake. Let the powder dissolve fully before drawing.
  2. 2Draw your dose. For subcutaneous injection, use a 29 to 31 gauge insulin syringe (U-100). 200 mcg equals 8 IU. 300 mcg equals 12 IU. 500 mcg equals 20 IU. For intranasal, transfer the reconstituted solution to a calibrated nasal atomizer or use a pre-made spray.
  3. 3Subcutaneous route: clean the injection site (abdomen or thigh) with an alcohol swab. Pinch the skin and insert the needle at a 45-degree angle. Inject slowly and withdraw. Rotate injection sites between doses. Onset is approximately 30 minutes.
Full injection guide →
Need a different vial size? Open the universal Semax reconstitution calculator to enter any vial mg + BAC water mL.

Semax Dosing Protocol

CommunityCommunity dosing consensus from peptide research communities
LevelDose / InjectionFrequency
Beginner200 mcgDaily
Moderate500 mcgDaily
Aggressive1 mgDaily
Note:

Reconstitution math for the standard setup: 5 mg vial plus 2 mL bacteriostatic water gives you 2500 mcg/mL. On a U-100 insulin syringe, 200 mcg is 8 IU, 300 mcg is 12 IU, 400 mcg is 16 IU, 500 mcg is 20 IU. For pre-made nasal spray (common at 30 mg/10 mL = 3000 mcg/mL), verify the mcg-per-spray on the label before dosing. Spray calibration varies between atomizers. Morning only. Nothing after noon. The dopaminergic tail will disrupt your sleep if you dose late. This is the single most common correctable complaint in community reports. Start at 200 mcg. Assess tolerance for 3 days before moving to 300 mcg. The response curve is clear in the community data; 300 to 500 mcg is where most users settle. If you feel nothing by day 5, check three things. Is the vial refrigerated and under 21 days post-reconstitution? Is the reconstitution volume correct (a dilution error is the most common source problem)? Did you actually dose in the morning on an empty stomach? Advancing to 400 mcg is reasonable after ruling those out. Stacking with Selank 300 mcg intranasal takes the edge off for users sensitive to the dopaminergic stimulation. That combination is the community default for good reason.

Dosing based on Community dosing consensus from peptide research communities: 9 published references.View all sources →

How the Semax Math Works

5mg in 2mL
=2.5mg/mL
2.5mg/mL
=25 mcg per unit
200 mcg / 25
=8 units
5mg / 200 mcg
=25 doses

Based on a 5mg vial, 2mL of bacteriostatic water, the beginner dose (200 mcg), and a U-100 syringe. Change any input in the calculator and every line moves with it.

Verify your calculation

Cross-check your Semax reconstitution math with AI

Semax Cost

Generic / Research
5 mg lyophilized powder vial: ~$30–$35 USD. 30 mg bulk: ~$72–$76 USD (research-grade market range). Approx $/mg: ~$6–$7 at 5mg tier; ~$2.40–$2.50 at 25–30mg tier.
Compounded
Research-grade nasal spray 10 mL/30 mg: ~$77 USD (typical research-grade price). Compounded pharmacy (if FDA adds it to the 503A bulks list): estimated $80–$150/month per community reports. Listed as withdrawn from Category 2 as of April 22, 2026. PCAC discussed it on July 24, 2026; no FDA rule has added it to the 503A bulks list.

Pricing updated 2026-04-09

Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →

Semax Pharmacokinetics

Pharmacokinetics: Active Dose Over Time

t½ = ~2-3 min (IV)
50%25%12.5%100%75%50%25%0%03m5m8m10m12mTime after injectionDose remaining
After 1 half-life (3m): 50% remainsAfter 2 half-lives (5m): 25% remainsAfter 3 half-lives (8m): 12.5% remains
At a 500 mcg dose: 50% = 250 mcg remaining after 3m. Recommended frequency: Daily.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only, not medical advice.

Read the full Semax guide →Best Peptides for Cognitive Enhancement →

Comparing Options?

Related Tools

Frequently Asked Questions

It depends on your vial size, BAC water, and dose. For a 5mg vial with 2mL BAC water, a beginner dose of 200mcg is typically 8 units on a U-100 syringe. Use the calculator above for your exact numbers.

The standard amount is 2mL of bacteriostatic water for a 5mg vial. More water gives a more dilute solution, so the same dose fills more of the syringe and is easier to measure. Less water makes the draw smaller and harder to read. The number of doses per vial does not change either way, since that depends only on vial size and dose. Adjust the BAC water slider in the calculator to see how it changes your syringe units.

At a beginner dose of 200mcg daily, a 5mg vial lasts about 25 doses. The calculator shows exact doses per vial for your selected tier.

Most people use a 1mL U-100 insulin syringe (100 units). For very small doses, a 0.5mL or 0.3mL barrel is easier to read. All three are U-100 graduated, so the number of units to draw is the same on each. Veterinary U-40 syringes are a different scale and the calculator adjusts for that separately.

Store reconstituted Semax at 2-8°C (36-46°F). Refrigerate at 2-8°C, use within 3-4 weeks. Nasal spray: refrigerate after opening, use within 30 days. Unopened vials: Store at 2-8°C, stable up to 2 years sealed.