Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 7, 20269 Citations
Semax Dosage Calculator
Cognitive · Research · Grade B · ~2-3 min half-life · Injection / Nasal
Calculate your dose
Adjust vial, water and dose. The answer updates live.
All three take the same units for the same dose. A smaller barrel just spreads it over more space.
on a U-100 syringe for a 200 mcg dose
Add 2 mL BAC water to your 5 mg vial. Draw to 8.0 units on a U-100 syringe for a 200 mcg dose. This vial will last 25 doses.
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Dose math and a schedule you can keep.
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What you need to mix this6 items, matched to your vial, BAC water and syringe
- Semax, 5 mg vialThe vial size set in the calculator.
- Bacteriostatic water, 2 mLPrescription-only in the US, so it is dispensed by a pharmacy on a clinician's prescription.
- 1 mL U-100 insulin syringe (100 units)Matches the syringe set in the calculator. Use a new sterile one for every injection.
- Alcohol swabsFor each vial stopper every time a needle goes in, and for the injection site. Let the alcohol dry first.
- A sharps containerUsed syringes go in right after each injection, never loose in the trash.
- Storage after mixingRefrigerate at 2-8°C, use within 3-4 weeks. Nasal spray: refrigerate after opening, use within 30 days.
How to choose each item: the peptide supplies guide.
About Semax
Turns your vial size, BAC water, and dose into exact syringe units. Free to use.
Semax triples hippocampal BDNF in rodent models and is approved for stroke recovery in Russia. Short 10 to 20 day intranasal or subcutaneous cycles produce focus and memory benefits that persist weeks after stopping. No RCTs in healthy adults exist.
View side effects and safety warnings →
Quick-Start: Reconstitution
- 1Reconstitute the vial. Add 2 mL of bacteriostatic water to a 5 mg Semax vial. This gives you 2500 mcg/mL. Swirl gently, do not shake. Let the powder dissolve fully before drawing.
- 2Draw your dose. For subcutaneous injection, use a 29 to 31 gauge insulin syringe (U-100). 200 mcg equals 8 IU. 300 mcg equals 12 IU. 500 mcg equals 20 IU. For intranasal, transfer the reconstituted solution to a calibrated nasal atomizer or use a pre-made spray.
- 3Subcutaneous route: clean the injection site (abdomen or thigh) with an alcohol swab. Pinch the skin and insert the needle at a 45-degree angle. Inject slowly and withdraw. Rotate injection sites between doses. Onset is approximately 30 minutes.
Semax Dosing Protocol
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 200 mcg | Daily |
| Moderate | 500 mcg | Daily |
| Aggressive | 1 mg | Daily |
Reconstitution math for the standard setup: 5 mg vial plus 2 mL bacteriostatic water gives you 2500 mcg/mL. On a U-100 insulin syringe, 200 mcg is 8 IU, 300 mcg is 12 IU, 400 mcg is 16 IU, 500 mcg is 20 IU. For pre-made nasal spray (common at 30 mg/10 mL = 3000 mcg/mL), verify the mcg-per-spray on the label before dosing. Spray calibration varies between atomizers. Morning only. Nothing after noon. The dopaminergic tail will disrupt your sleep if you dose late. This is the single most common correctable complaint in community reports. Start at 200 mcg. Assess tolerance for 3 days before moving to 300 mcg. The response curve is clear in the community data; 300 to 500 mcg is where most users settle. If you feel nothing by day 5, check three things. Is the vial refrigerated and under 21 days post-reconstitution? Is the reconstitution volume correct (a dilution error is the most common source problem)? Did you actually dose in the morning on an empty stomach? Advancing to 400 mcg is reasonable after ruling those out. Stacking with Selank 300 mcg intranasal takes the edge off for users sensitive to the dopaminergic stimulation. That combination is the community default for good reason.
Dosing based on Community dosing consensus from peptide research communities: 9 published references.View all sources →
How the Semax Math Works
- 5mg in 2mL
- =2.5mg/mL
- 2.5mg/mL
- =25 mcg per unit
- 200 mcg / 25
- =8 units
- 5mg / 200 mcg
- =25 doses
Based on a 5mg vial, 2mL of bacteriostatic water, the beginner dose (200 mcg), and a U-100 syringe. Change any input in the calculator and every line moves with it.
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Semax Cost
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Semax Pharmacokinetics
Pharmacokinetics: Active Dose Over Time
t½ = ~2-3 min (IV)Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only, not medical advice.